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Ching-Feng Weng, Professor 翁慶豐

Ching-Feng Weng, Professor, PhD

PhD in Physiology, 1994

University of Maryland at Baltimore, USA

E-Mail: cfweng@gms.ndhu.edu.tw

Tel: 886-3-8903637; Fax: 886-3-8900163

Research Interests:

1. Chinese medicine and herbs

2. Molecular physiology

3. Liver fibrosis and regeneration.

Experiences

1978-1981

Veterinary doctor, Taiwan Sugar Company, Taiwan

1981-1985

Assistant Researcher, Taiwan Pig research Institute, Taiwan

1983-1985

Adjutant Editor, China Animal science Society, Taiwan

1985-1988

Research Associate, Institute of Zoology, Academia Sinica, Taiwan

1992-1994

Assistant Researcher, Department of Pathology, Waltereed Army Hospital, USA

1994-1998

Post-doctor Fellow, Institute of. Zoology, Academia Sinica, Taiwan

1998-1998

Associate Researcher and Production Chief, National Laboratory Animal Center, Taiwan

1998-2000

Post-doctor Fellow, Institute of Zoology, Academia Sinica, Taiwan

2000-2003

Assistant Professor, Department of Life Science and Graduate Inst Biotechnology, National Dong-Hwa University

2003-2007

Associate Professor, Department of Life Science and Graduate Inst Biotechnology, National Dong-Hwa University

2007-2009

Professor, Department of Life Science and Graduate Inst Biotechnology, National Dong-Hwa University

2009-2013

Chairman, Department of Life Science and Graduate Inst Biotechnology, National Dong-Hwa University

SCI Journals

  1. Thiyagarajan V, Lee KW, Leong MK, Weng CF. (2017) Potential natural mTOR inhibitors screened by in silico approach and suppress hepatic stellate cells activation. J Biomol Struct Dyn. 28:1-52. doi: 10.1080/07391102.2017.1411295 (correspondent author)
  2. Yu-Hsin Chen, Juan-Cheng Yang, Mei-Chin Lu, Ching-Feng Weng, Yin-Di Su, Jimmy Kuo, Yang-Chang Wu, Ping-Jyun Sung (2017). Bafilomycins N and O, novel cytotoxic bafilomycin analogues produced by Streptomyces sp. GIC10-1 isolated from marine sponge Theonella sp. Tetrahedron 73: 5170-5175
  3. Yu-Hsin Chen, Wu-Fu Chen, Juan-Cheng Yang, Mei-Chin Lu, Jimmy Kuo, Jui-Hsin Su, Ching-Feng Weng, Yang-Chang Wu, Ping-Jyun Sung (2017). Pseudoalteromone C: a novel ubichromenol derivative from bacterium Pseudoalteromonas sp. CGH2XX isolated from the cultured-type Octocoral Lobophytum crassum. Natural Product Communications 12:1615-1617.
  4. Tseng FJ, Chia WT, Pan RY, Lin LC, Shen HC, Wang CH, Shyu JF, Weng CF.( 2017) Comparison of arthroplasty vs. osteosynthesis for displaced femoral neck fractures: a meta-analysis. J Orthop Surg Res. 12(1):131. doi: 10.1186/s13018-017-0629-5. (correspondent author)
  5. Tsai MJ, Huang CT, Huang YS, Weng CF, Shyue SK, Huang MC, Liou DY, Lin YR, Cheng CH, Kuo HS, Lin Y, Lee MJ, Huang WH, Huang WC, Cheng H. (2017) Improving the regenerative potential of olfactory ensheathing cells by overexpressing prostacyclin synthetase and its application in spinal cord repair. J Biomed Sci. 24(1):34. doi: 10.1186/s12929-017-0340-1.
  6. Cheng MF, Lin SR, Tseng FJ, Huang YC, Tsai MJ, Fu YS, Weng CF (2017) The autophagic inhibition oral squamous cell carcinoma cancer growth of 16-hydroxycleroda-3,13-dien-15,16-olide; Oncotarget;. 8(45):78379-78396. (correspondent author)
  7. Huang PK, Lin SX, Tsai MJ, Leong MK, Lin SR, Kankala RK, Lee CH, Weng CF. (2017) Encapsulation of 16-Hydroxycleroda-3,13-Dien-16,15-Olide in Mesoporous Silica Nanoparticles as a Natural Dipeptidyl Peptidase-4 Inhibitor Potentiated Hypoglycemia in Diabetic Mice. Nanomaterials (Basel) 7(5). pii: E112. doi: 10.3390/nano7050112. (correspondent author)
  8. Cheng MF, Lin CS, Chen YH, Sung PJ, Lin SR, Tong YW, Weng CF (2017) Inhibitory Growth of Oral Squamous Cell Carcinoma Cancer via Bacterial Prodigiosin; Mar. Drugs; 15(7), 2017, 224. (correspondent author)
  9. Lin SR, Fu YS, Tsai MJ, Cheng H, Weng CF ( 2017) Natural Compounds from Herbs that can Potentially Execute as Autophagy Inducers for Cancer Therapy; Int. J. Mol. Sci. 18(7), pii: E1412. (correspondent author)
  10. Kalai Selvi S, Vinoth A, Varadharajan T, Weng CF, Vijaya Padma V. (2017). Neferine augments therapeutic efficacy of cisplatin through ROS- mediated non-canonical autophagy in human lung adenocarcinoma (A549 cells). Food Chem Toxicol. 103:28-40. doi: 10.1016/j.fct.2017.02.020. (equal correspondent author)
  11. Sivalingam KS, Paramasivan P, Weng CF, Vijaya Padma V. (2017). Neferine Potentiates the Antitumor Effect of Cisplatin in Human Lung Adenocarcinoma Cells via a Mitochondria-mediated Apoptosis Pathway. J Cell Biochem. 118(9):2865-2876. doi: 10.1002/jcb.25937. (equal correspondent author)
  12. Lee DN, Hung YS, Yang TS, Lin JH, Weng CF. (2017) Aspergillus awamori-fermented mung bean seed coats enhance the antioxidant and immune responses of weaned pigs. J Anim Physiol Anim Nutr (Berl). 101(5):e342-e351. doi: 10.1111/jpn.12611. (correspondent author)
  13. Leong MK, Syu RG, Ding YL, Weng CF. (2017)  Prediction of N-Methyl-D-Aspartate Receptor GluN1-Ligand Binding Affinity by a Novel SVM-Pose/SVM-Score Combinatorial Ensemble Docking Scheme. Sci Rep. 7:40053. doi: 10.1038/srep40053. (equal correspondent author)
  14. Ma YD, Thiyagarajan V, Tsai MJ, Lue SI, Chia YC, Shyue SK, Weng CF. (2016) Pyrogallol abates VSMC migration via modulation of Caveolin-1, matrix metalloproteinase and intima hyperplasia in carotid ligation mouse. Environ Toxicol Pharmacol. 48:63-75. doi: 10.1016/j.etap.2016.10.005. (correspondent author)
  15. Chen LH, Hsu WL, Tseng YJ, Liu DW, Weng CF. (2016) Involvement of DNMT 3B promotes epithelial-mesenchymal transition and gene expression profile of invasive head and neck squamous cell carcinomas cell lines.BMC Cancer. 16:431. doi: 10.1186/s12885-016-2468-x. Erratum in: BMC Cancer. 16(1):595. (correspondent author)
  16. Thiyagarajan V, Sivalingam KS, Viswanadha VP, Weng CF. (2016) 16-hydroxy-cleroda-3,13-dien-16,15-olide induced glioma cell autophagy via ROS generation and activation of p38 MAPK and ERK-1/2. Environ Toxicol Pharmacol.45:202-11. doi: 10.1016/j.etap.2016.06.005. (correspondent author)
  17. Thiyagarajan, V., Lin, S.H., Chang, Y.C., Weng CF. (2016). Identification of novel FAK and S6K1 dual inhibitors from natural compounds via ADMET screening and molecular docking. Biomedicine & Pharmacotherapy 80: 5262 (correspondent author).
  18. Thiyagarajan, V., Lin, S.X., Lee, C.H., Weng CF. (2016) A focal adhesion kinase inhibitor 16-hydroxy-cleroda-3,13-dien-16,15-olide incorporated into enteric-coated nanoparticles for controlled anti-glioma drug delivery. Colloids Surf B Biointerfaces. 141:120-131. doi: 10.1016/j.colsurfb.2016.01.038. (correspondent author)
  19. Velmurugan, B.K., Yang, H.H., Sung, P.J., Weng CF. (2016) Excavatolide B inhibits nonsmall cell lung cancer proliferation by altering peroxisome proliferator activated receptor gamma expression and PTEN/AKT/NF-Kβ expression. Environ Toxicol. 32(1):290-301. doi: 10.1002/tox.22235. (correspondent author)
  20. Chen ZA, Kuthati Y, Kankala RK, Chang YC, Liu CL, Weng CF, Mou CY, Lee CH. (2015) Encapsulation of palladium porphyrin photosensitizer in layered metal oxide nanoparticles for photodynamic therapy against skin melanoma. Sci Technol Adv Mater. Oct 9;16(5):054205.
  21. Kankala, R. K., Kuthati, Y., Sie, H. W., Shih, H. Y., Lue, S. I., Kankala, S., Jeng, C. C., Deng, J. P., Weng CF, Liu, C. L., Lee, C. H. (2015). Multi-laminated metal hydroxide nanocontainers for oral-specific delivery for bioavailability improvement and treatment of inflammatory paw edema in mice. J Colloid Interface Sci, 458, 217-228. doi:10.1016/j.jcis.2015.07.044
  22. Jhong, C. H., Riyaphan, J., Lin, S. H., Chia, Y. C., Weng CF (2015). Screening alpha-glucosidase and alpha-amylase inhibitors from natural compounds by molecular docking in silico. Biofactors, 41(4), 242-251. doi:10.1002/biof.1219 (correspondent author)
  23. Kuthati, Y., Kankala, R.K., Lin, S.X., Weng CF, Lee, C.H. (2015). pH-Triggered Controllable Release of Silver-Indole-3 Acetic Acid Complexes from Mesoporous Silica Nanoparticles (IBN-4) for Effectively Killing Malignant Bacteria. Mol Pharm, 12(7), 2289-2304. doi:10.1021/mp500836w
  24. Lin, S. H., Huang, K. J., Weng CF, Shiuan, D. (2015). Exploration of natural product ingredients as inhibitors of human HMG-CoA reductase through structure-based virtual screening. Drug Des Devel Ther, 9, 3313-3324. doi:10.2147/DDDT.S84641
  25. Sulake, R. S., Lin, H. H., Hsu, C. Y., Weng CF, Chen, C. (2015). Synthesis of (+)-Antroquinonol: An Antihyperglycemic Agent. J Org Chem, 80(12), 6044-6051. doi:10.1021/acs.joc.5b00345(correspondent author)
  26. Thiyagarajan, V., Tsai, M. J., Weng CF. (2015). Antroquinonol Targets FAK-Signaling Pathway Suppressed Cell Migration, Invasion, and Tumor Growth of C6 Glioma. PLoS One, 10(10), e0141285. doi:10.1371/journal.pone.0141285 (SCI, 3.534; ranking 8/55) (correspondent author).
  27. Tseng, F. J., Chia, W. T., Wang, C. H., Shyu, J. F., Gou, G. H., Shui, H. A., Sytwu, H. K., Pan, R. Y., Weng CF. (2015). Carbon Monoxide Inhibits Receptor Activator of NF-kappaB (RANKL)-Induced Osteoclastogenesis. Cell Physiol Biochem, 36(3), 1250-1258. doi:10.1159/000430294 (correspondent author).
  28. Wang, K. H., Lin, C. J., Liu, C. J., Liu, D. W., Huang, R. L., Ding, D. C., Weng CF. Chu, T. Y. (2015). Global methylation silencing of clustered proto-cadherin genes in cervical cancer: serving as diagnostic markers comparable to HPV. Cancer Med, 4(1), 43-55. doi:10.1002/cam4.335
  29. Chen  LH, Liu  DW, Chang  JL, Chen  PR, Hsu  LP, Lin  HY, Chou  YF, Lee  CF, Yang  MC, Wen  YH, Hsu  WL, Weng  CF. (2015) Methylation status of insulin-like growth factor-binding protein 7 concurs with the malignance of oral tongue cancer. J Experimental & Clinical Cancer Research  34:20 doi:10.1186/s13046-015-0138-5 (SCI, 3.27; ranking 76/203) (correspondent author).
  30. Hsu CY, Shih HY, Chang YC, Huang ZL, Tsai MJ, Chia YC, Chen C, Lai YK, Weng CF. (2015) The beneficial effects of tetracosanol on insulin-resistance by insulin receptor kinase sensibilization. J. Funct. Foods 14:174-182. 10.1016/j.jff.2015.01.033 (SCI, 4.480; ranking 5/123) (correspondent author).
  31. Wang KH, Lin CJ, Liu CJ, Liu DW, Huang RL, Ding DC, Weng CF, Chu TY.  (2015) Global methylation silencing of clustered proto-cadherin genes in cervical cancer: serving as diagnostic markers comparable to HPV. Cancer Med. 4(1):43-55. doi: 10.1002/cam4.335.  
  32. Wu TF, Luo FJ, Chang YL, Huang CM, Chiu WJ, Weng CF, Hsu YK, Yuan TC. (2015) The oncogenic role of androgen receptors in promoting the growth of oral squamous cell carcinoma cells. Oral Dis. 21(3):320-7. doi: 10.1111/odi.12272. (SCI, 2.404; ranking 14/83).
  33. Hsu CY, Sulake RS, Huang PK, Shih HY, Sie HW, Lai YK, Chen C, Weng CF. (2015) Synthetic of (+)-antroquinonol possesses dual efficacy for insulin-resistance via triggering AMPK and anti- DPP IV activity. Br J Pharmacol. 172(1):38-49. doi: 10.1111/bph.12828 (SCI, 4.990; ranking 21/256 ) (equal correspondent author).
  34. Chen SF, Chao YL, Shen YC, Chen CH, Weng CF. (2014) Resequencing and association study of the NFKB activating protein-like gene (NKAPL) in schizophrenia. Schizophr Res. pii: S0920-9964(14)00294-1. doi: 10.1016/j.schres.2014.05.038 (SCI, 4.426; ranking 22/136) (correspondent author).
  35. Lee KW, Thiyagarajan V, Sie HW, Cheng MF, Tsai MJ, Chia YC, Weng CF. (2014) Synergistic effect of natural compounds on the fatty acid-induced autophagy of activated hepatic stellate cells. J Nutr Biochem. pii: S0955-2863(14)00082-5. doi: 10.1016/j.jnutbio.2014.04.001 (SCI, 4.592 ; ranking 9/79 ) (correspondent author).
  36. Yu TL, Lin HD, Weng CF. (2014) A new phylogeographic pattern of endemic Bufo bankorensis in Taiwan Island is attributed to the genetic variation of populations. PLoS One. 9(5):e98029. doi: 10.1371/journal.pone.0098029. eCollection 2014 (SCI, 3.534 ; ranking 8/55 ) (correspondent author).
  37. Tang ZJ, Lue SI, Tsai MJ, Yu TL, Thiyagarajan V, Lee CH, Huang WT, Weng CF. (2014) The hormonal regulation of color changes in the sexually dichromatic frog Buergeria robusta. Physiol Biochem Zool. 87(3):397-410. doi: 10.1086/675678 (SCI, 2.050 ; ranking 25/153) (correspondent author).
  38. Chen YR, Chang KT, Tsai MJ, Lee CH, Huang KJ, Cheng H, Ho YP, Chen JC, Yang HH, Weng CF. (2014) Antrodia cinnamomea profoundly exalted the reversion of activated hepatic stellate cells by the alteration of cellular proteins. Food Chem Toxicol. 69:150-62. doi: 10.1016/j.fct.2014.04.006 (SCI, 2.610; ranking 21/123) (correspondent author).
  39. Sheu JH, Chen YH, Chen YH, Su YD, Chang YC, Su JH, Weng CF, Lee CH, Fang LS, Wang WH, Wen ZH, Wu YC, Sung PJ. (2014) Briarane diterpenoids isolated from gorgonian corals between 2011 and 2013. Mar Drugs. 12(4):2164-81. doi: 10.3390/md12042164 (SCI, 7,326; ranking 3/87).
  40. Hsu CY, Shih HY, Chia YC, Lee CH, Ashida H, Lai YK, Weng CF. (2014) Rutin potentiates insulin receptor kinase to enhance insulin-dependent glucose transporter 4 translocation. Mol Nutr Food Res. 58(6):1168-76. doi: 10.1002/mnfr.201300691(SCI, 4.909; ranking 3/123) (equal correspondent author).
  41. Lin YC, Chen LH, Varadharajan T, Tsai MJ, Chia YC, Yuan TC, Sung PJ, Weng CF. (2014) Resveratrol inhibits glucose-induced migration of vascular smooth muscle cells mediated by focal adhesion kinase. Mol Nutr Food Res. 58(7):1389-401. doi: 10.1002/mnfr.201300698(SCI, 4.909; ranking 3/123) (correspondent author).
  42. Poornima P, Kumar VB, Weng CF, Padma VV. (2014) Doxorubicin induced apoptosis was potentiated by neferine in human lung adenocarcima, A549 cells. Food Chem Toxicol. 68:87-98. doi: 10.1016/j.fct.2014.03.008 (SCI, 2.610; ranking 21/123) (equal correspondent author).
  43. Poornima P, Weng CF, Padma VV. (2014) Neferine, an alkaloid from lotus seed embryo, inhibits human lung cancer cell growth by MAPK activation and cell cycle arrest. Biofactors. 40(1):121-31. doi: 10.1002/biof.1115 (SCI, 3.000; ranking 57/124)(equal correspondent author).
  44. Chen CC, Li KW, Yu TL, Chen LH, Sheu PY, Tong YW, Huang KJ, Weng CF. (2013) Genetic structure of Bufo bankorensis distinguished by amplified restriction fragment length polymorphism of cytochrome b. Zoological Studies. 52:48-57 (SCI, 1.014; ranking 76/153) (correspondent author).
  45. Hsu YJ, Weng CF, Lin KW, Lin KC.(2013) Suppression of allergic reactions in ovalbumin-sensitized mice by yam storage proteins dioscorins. J Agric Food Chem. 61(47):11460-7. doi: 10.1021/jf403480s (SCI, 3.107; ranking 13/123).
  46. Poornima P, Weng CF, Padma VV. (2013) Neferine from Nelumbo nucifera induces autophagy through the inhibition of PI3K/Akt/mTOR pathway and ROS hyper generation in A549 cells. Food Chem. 141(4):3598-605. doi: 10.1016/j.foodchem.2013.05.138 (SCI, 3.259; ranking 10/123) (equal correspondent author).
  47. Kuthati Y, Sung PJ, Weng CF, Mou CY, Lee CH. (2013) Functionalization of mesoporous silica nanoparticles for targeting, biocompatibility, combined cancer therapies and theragnosis. J Nanosci Nanotechnol. 13(4):2399-430. Review (SCI, 1.339; ranking 51/73).
  48. Tsai MJ, Weng CF, Yu NC, Liou DY, Kuo FS, Huang MC, Huang WC, Tam K, Shyue SK, Cheng H. (2013) Enhanced prostacyclin synthesis by adenoviral gene transfer reduced glial activation and ameliorated dopaminergic dysfunction in hemiparkinsonian rats. Oxid Med Cell Longev. 2013:649809. doi: 10.1155/2013/649809 (SCI, 3.363; ranking 91/185).
  49. Thiyagarajan V, Lin SH, Chia YC, Weng CF. (2013) A novel inhibitor, 16-hydroxy-cleroda-3,13-dien-16,15-olide, blocks the autophosphorylation site of focal adhesion kinase (Y397) by molecular docking. Biochim Biophys Acta. 1830(8):4091-101. doi: 10.1016/j.bbagen.2013.04.027 (SCI, 5.440; ranking 48/291) (correspondent author).
  50. Lin CY, Lu MC, Su JH, Chu CL, Shiuan D, Weng CF, Sung PJ, Huang KJ. (2013) Immunomodulatory effect of marine cembrane-type diterpenoids on dendritic cells. Mar Drugs.11(4):1336-50. doi: 10.3390/md11041336 (SCI, 7,326; ranking 3/87).
  51. Yen WH, Hu LC, Su JH, Lu MC, Twan WH, Yang SY, Kuo YC, Weng CF, Lee CH, Kuo YH, Sung PJ. (2012) Norcembranoidal diterpenes from a Formosan soft coral Sinularia sp. Molecules. 17(12):14058-66. doi: 10.3390/molecules171214058 (SCI, 2.095; ranking 30/58).
  52. Chen YH, Kuo J, Sung PJ, Chang YC, Lu MC, Wong TY, Liu JK, Weng CF, Twan WH, Kuo FW. (2012) Isolation of marine bacteria with antimicrobial activities from cultured and field-collected soft corals. World J Microbiol Biotechnol. 28(12):3269-79. doi: 10.1007/s11274-012-1138-7 (SCI, 3.023; ranking 40/119).
  53. Yu-Hsin Chen, Mei-Chin Lu, Yu-Chia Chang, Tsong-Long Hwang, Wei-Hsien Wang, Ching-Feng Weng, Jimmy Kuo, Ping-Jyun Sung (2012) Pseudoalteromone A: A novel bioactive ubiquinone from a marine bacterium Pseudoalteromonassp. CGH2XX (Pseudoalteromonadaceae). Tetrahedron Lett, (SCI, 2.618; ranking: 20/56) (equal correspondent author).
  54. Chen YH, Kuo J, Su JH, Hwang TL, Chen YH, Lee CH, Weng CF, Sung PJ.(2012) Pseudoalteromone B: a novel 15C compound from a marine bacterium Pseudoalteromonas sp. CGH2XX. Mar Drugs. 10(7):1566-71. doi: 10.3390/md10071566 (SCI, 3.512; ranking 10/58) (equal correspondent author).
  55. Hong PH, Su YD, Su JH, Chen YH, Hwang TL, Weng CF, Lee CH, Wen ZH, Sheu JH, Lin NC, Kuo YH, Sung PJ. (2012) Briarenolides F and G, new briarane diterpenoids from a Briareum sp. octocoral. Mar Drugs. 10(5):1156-68. doi: 10.3390/md10051156 (SCI, 7,326; ranking 3/87).
  56. Lin CH, Cheng SH, Liao WN, Wei PR, Sung PJ, Weng CF, Lee CH. (2012) Mesoporous silica nanoparticles for the improved anticancer efficacy of cis-platin. Int J Pharm. 429(1-2):138-47. doi: 10.1016/j.ijpharm.2012.03.026 (SCI, 3.785; ranking 45/256).
  57. Wei PR, Cheng SH, Liao WN,  Kao KC, Weng CF, Lee CH. (2012) Synthesis of chitosan-coated near-infrared layered double hydroxide nanoparticles for in vivo optical imaging. J. Mater. Chem., 22: 5503-5513. DOI: 10.1039/C2JM16447G (SCI, 6.626; ranking 22/251).
  58. Pei-Ru Wei, Shih-Hsun Cheng, Wei-Neng Liao, Kun-Che Kao, Ching-Feng Weng, Chia-Hung Lee (2012) Synthesis of chitosan-coated near-infrared layered double hydroxide nanoparticles for in vivo optical imaging. J. Mater. Chem. (SCI, 4.339; Ranking: 14/190). DOI: 10.1039/C2JM16447G
  59. Kao CY, Su JH, Lu MC, Hwang TL, Wang WH, Chen JJ, Sheu JH, Kuo YH, Weng CF, Fang LS, Wen ZH & Sung PJ. (2011) Lobocrassins A-E: New cembrane-type diterpenoids from the soft coral Lobophytum crassum. Mar Drugs 9(8):1319-31 (SCI, 3.471; ranking 4/46).
  60. Chen YH, Tai CY, Su YD, Chang YC, Lu MC, Weng CF, Su JH, Hwang TL, Wu YC & Sung PJ. (2011) Discovery of new eunicellins from an Indonesian octocoral Cladiella sp. Mar Drugs 9(6):934-43 (SCI, 3.471; ranking 4/46).
  61. Kumar VB, Yuan TC, Liou JW, Yang CJ, Sung PJ & Weng CF. (2011) Antroquinonol inhibits NSCLC proliferation by altering PI3K/mTOR proteins and miRNA expression profiles. Mutat Res. 707: 42–52 (SCI, 3.556; ranking 10/77)(correspondent author).
  62. Yung-Husan Chen, Chia-Ying Tai, Tsong-Long Hwang, Ching-Feng Weng, Jan-Jung Li, Lee-Shing Fang, Wei-Hsien Wang, Yang-Chang Wu & Ping-Jyun Sung (2010) Cladielloides A and B: New eunicellin-type diterpenoids from an Indonesian Octocoral Cladiella sp. Mar. Drugs, 8: 2936-2945 (SCI, 2.863; ranking 16/46).
  63. May-Jywan Tsai, Hsu-An Pan, Dann-Ying Liou, Ching-Feng Weng, Barry J. Hoffer & Henrich Cheng (2010) Adenoviral gene transfer of bone morphogenetic protein-7 enhances functional recovery after sciatic nerve injury in rats. Gene therapy 17(10): 1214-1224 (SCI 4.492; ranking 10/83) (correspondent author).
  64. Ping-Jyun Sung, Gung-Ying Li, Yin-Di Su, Mei-Ru Lin, Yu-Chia Chang, Ting-Hsuan Kung, Chan-Shing Lin, Yung-Husan Chen, Jui-Hsin Su, Mei-Chin Lu, Jimmy Kuo, Ching-Feng Weng & Tsong-Long Hwang (2010) Excavatoids O and P, New 12-hydroxybriaranes from the Octocoral Briareum excavatum. Mar. Drugs 8: 2639-2646 (SCI, 2.863; ranking 16/46).
  65. Ping-Jyun Sung, Su-Hui Wang, Yu-Chia Chang, Yung-Husan Chen, Mei-Ru Lin, I-Chu Huang, Jih-Jung Chen, Jan-Jung Li, Ting-Hsuan Kung, Lee-Shing Fang, Wei-Hsien Wang & Ching-Feng Weng (2010) New briarane-related diterpenoids from the Sea Whip Gorgonian Coral Junceella fragilis (Ellisellidae). Chem. Pharmaco. Bull. 83: 1074-1078 (SCI 1.623; ranking 23/41).
  66. Huang WT & Weng CF. (2010) Roles of hepatocyte nuclear factors (HNF) in the regulation of reproduction in teleosts.  J. Fish. Biol. 76(1): 225-39 (SCI 1.226; ranking 22/42) (correspondent author).
  67. Wang SH, Chang YC, Chiang MY, Chen YH, Hwang TL, Weng CF & Sung PJ. (2010) Chlorinated briarane diterpenoids from the sea whip gorgonian corals Junceella fragilis and Ellisella robusta (Ellisellidae). Chem. Pharm. Bull. (Tokyo). 58(7): 928-33 (SCI 1.623; ranking 23/41).
  68. Chih-Jen Yang, Chuan-Sheng Wang, I-Chun Chuang, Jen-Yu Hung, Cheng-Yuan Wang, Yu-Jung Huang, Pei-Hui Wang, Tung-Heng Wang, Hseng-Kuang Hsu, May-Jywan Tsai, Yu-chu Chen, V. Bharath Kumar, Ming-Shyan Huang & Ching-Feng Weng (2010) Anti-proliferative effect of Toona sinensis leaf extract on non-small cell lung cancer. Translational Res. 155(6): 305-14 (SCI, 1.984; ranking: 10/27) (correspondent author).
  69. Chih-Jen Yang, Yu-Jung Huang, Cheng-Yuan Wang, Chuan-Sheng Wang, Pei-Hui Wang, Jen-Yu Hung, Tung-Heng Wang, Hseng-Kuang Hsu, Hurng-Wern Huang, S.P. Anand Kumar, Ming-Shyan Huang & Ching-Feng Weng (2010) Antiproliferative and antitumorigenic activity of Toona sinensis leaf extracts in Lung Adenocarcinoma. J. Med. Food 13 (1): 1–8 (SCI, 1.288; ranking: 42/107) (correspondent author).
  70. Huai-En Lu, Chien-Huei Jian, Shu-Fen Chen, Tse-Min Chen, Son-Tay Lee, Chun-Sheng Chang & Ching-Feng Weng (2010) Hypoglycemic effects of solid-state fermented mycelium of Paecilomyces farinosus (G30801) on high-fat fed with streptozotocin-induced diabetes rat. Indian J. Med. Res. 131: 18-23 (SCI, 1.883; ranking: 48/82) (correspondent author).
  71. Chiung-Huei Peng,Yaw-Bee Ker, Ching-Feng Weng, Chiung-Chi Peng, Chien-Ning Huang, Li-Yun Lin & Robert Y. Peng (2009) Insulin secretagogue bioactivity of finger citron fruit (Citrus medica L. var. Sarcodactylis Hort, Rutaceae) J. Agric. Food Chem. 57(19): 8812-9 (SCI, 2.562; ranking: 10/107).
  72. Kai-Ting Chang, May-Jywan Tsai, Ya-Ting Cheng, Jyun-Jlang Chen, Ray-Hom Hsia, Yu-Shiu Lo, Yuan-Ron Ma & Ching-Feng Weng (2009) Comparative atomic force and scanning electron microscopy: an investigation of structural differentiation of hepatic stellate cells. J. Structure Biol. 167(3):200-8 (SCI, 4.059; ranking: 15/70) (correspondent author).
  73. Pei-Lan Lin, Kuo-Wei Lin, Ching-Feng Weng & Kuo-Chih Lin (2009) Yam storage protein dioscorins from Dioscorea alata and D. japonica exhibit distinct immunomodulatory activities in mice. J. Agric. Food Chem. 57(11): 4606-13 (SCI, 2.562; ranking: 10/107).
  74. V. Bharath Kumar, Ing-Fong Jiang, Hsueh-Hui Yang & Ching-Feng Weng (2009) Effects of serum on phagocytic activity and proteomic analysis of tilapia (Oreochromis mossambicus) serum after acute osmotic stress. Fish Shellfish Immunol. 26(5):760-7 (SCI, 3.161; ranking: 01/40) (correspondent author).
  75. Huang WT, Li CJ, Wu PJ, Chang YS, Lee TL & Weng CF (2009) Expression and in vitro regulation of pituitary adenylate cyclase-activating polypeptide (pacap38) and its type I receptor (pac1-r) in the gonads of tilapia (Oreochromis mossambicus). Reproduction 137: 449–467 (SCI, 3.073; ranking: 06/25) (correspondent author).
  76. Chih-Jen Yang, Chuan-Sheng Wang, Jen-Yu Hung, Hurng-Wern Huang, Yi-Chen Chia, Pei-Hui Wang, Ching-Feng Weng & Ming-Shyan Huang (2009) Pyrogallol induces G2-M arrest in human lung cancer cells and inhibits tumor growth in an animal model. Lung Cancer 66: 162–168 (SCI, 2.97; ranking: 63/141).
  77. Meng-Wen Yang,Wei-Tung Huang, May-Jywan Tsai, Ing-Fong Jiang & Ching-Feng Weng (2009) Transient response of brain heat shock protein 70 and 90 to acute osmotic stress in tilapia (Oreochromis mossambicus). Zoological Studies 48(6): 723-736 (SCI, 0.772; ranking: 82/124) (correspondent author).
  78. May-Jywan Tsai, Yi-Ming A. Chen, Ching-Feng Weng, Dann-Ying Liou, Hsin-Chun Yang, Chien-Hung Chen, Roanna I-Hsin Liao, Fu-Shan Kuo, Chiuan-Wen Chiu, Huai-Sheng Kuo, Ming-Chao Huang, Yi-Lo Lin, Meng-Jen Lee,Wen-Chun Kuo, Wen-Cheng Huang & Henrich Cheng (2009) Enhanced expression of glycine N-methyltransferase by adenovirus-mediated gene transfer in CNS culture is neuroprotective. Ann. N.Y. Acad. Sci. 1199: 194-203 (SCI, 2.303; ranking: 07/51).
  79. Wei-Tung Huang, Jung-Tsun Chien, Ching-Feng Weng, Yung-Yue Jeng, Li-Chia Lu &John Yuh-Lin Yu (2009) Ovine thyroid stimulating hormone (TSH) heterologously stimulates production of thyroid hormones from Chinese soft-shell turtle (Pelodiscus sinensis) and bullfrog (Rana catesbeiana and Rana rugulosa Wiegmann) thyroids in vitro. Comp. Biochem. Physiol. A Mol. Integr. Physiol. 153(2):167-73 (SCI, 1.709; ranking: 27/125).
  80. Ing-Fong Jiang, V. Bharath Kumar, D. N. Lee & C. F. Weng (2008) Acute osmotic stress affects Tilapia (Oreochromis mossambicus) innate immune responses. Fish Shellfish Immunol. 25(6): 841-6 (SCI, 3.161; ranking: 01/40) (correspondent author).
  81. Wang Pei-Hwei, May-Jwan Tsai, Chia-Yu Hsu, Chia-Yi Wang, Hseng-Kuang Hsu & Ching-Feng Weng (2008) Toona sinensis Roem (Meliaceae) leaf extract alleviates hyperglycemia via 3 altering adipose glucose transporter 4. Food Chem. Toxicol. 46(7):2554-60 (SCI, 2.321; ranking: 16/107) (correspondent author).
  82. Lee DN, Chuang YS, Chiou HY, Wu FY, Yen HT & Weng CF. (2008) Oral administration recombinant porcine epidermal growth factor enhances the jejunal digestive enzyme genes expression and activity of early-weaned piglets. J. Anim. Physiol. Anim. Nutr. (Berl). 92(4): 463-70 (SCI, 1.171; ranking: 17/45) (correspondent author).
  83. Chan CR., D. N. Lee, Y. H. Cheng, D. J.Y. Hsieh & C. F. Weng (2008) Feed deprivation (fasting) and re-feeding on the alterations of proteases in tilapia Oreochromic mossambicus. Zoological Studies 47: 207-214 (SCI, 0.772; ranking: 82/124) (correspondent author).
  84. Lee DN, Liu SR, Chen YT, Wang RC, Lin SY & Weng CF. (2007) Effects of diets supplemented with organic acids and nucleotides on growth, immune responses and digestive tract development in weaned pigs. J. Anim. Physiol. Anim. Nutr. (Berl). 91(11-12): 508-18 (SCI, 0.8091, ranking: 21/43) (correspondent author).
  85. Lee D. N., W. F. Chang, I.T. Yu, Peter W. S. Chiou & C. F. Weng (2007) Effects of diets supplemented with recombinant epidermal growth factor and glutamine on gastrointestinal tract development of early-weaned piglets. Asian-Aust. J. Anim. Sci. 21: 582-589 (SCI, 0.875, ranking: 18/43) (correspondent author).
  86. Wei-Tung Huang, Hao-Cheng Yu, Chih-Chien Hsu, Ching-Fong Liao, Hong-Yi Gong,  Cliff Ji-Fan Lin, Jen-Leih Wu & Ching-Feng Weng (2007) Steroid hormones (17 beta-estradiol and hydrocortisone) mediate hepatocyte nuclear factor (HNF)-3b and insulin-like growth factor I and II expression in the gonads of Tilapia (Oreochromis mossambicus). Theriogenology 68(7): 988-1002 (SCI, 1.898; ranking: 15/24) (correspondent author).
  87. Fan S, Chen HN, Wang CJ, Tseng WC, Hsu HK & Weng CF. (2007) Toona sinensis Roem (Meliaceae) leaf extract alleviates liver fibrosis via reducing TGF beta1 and collagen. Food Chem. Toxicol. 45(11): 2228-36 (SCI, 2.393; ranking: 07/96) (correspondent author).
  88. Tsai MJ, Weng CF, Shyue SK, Liou DY, Chen CH, Chiu CW, Yang TH, Pan HA, Liao RI, Kuo HS, Huang MC, Huang WC, Hoffer BJ & Cheng H (2007) Dual effect of adenovirus-mediated transfer of BMP7 in mixed neuron-glial cultures: Neuroprotection and cellular differentiation. J Neurosci. Res. 85(13): 2950-9 (SCI, 3.476; ranking: 58/199).
  89. Chen HN, Fan S & Weng CF (2007) Down-regulation of TGF beta 1 and leptin ameliorates thioacetamide-induced liver injury in lipopolysaccharide-primed rats. J. Endotoxin. Res. 13: 176-88. (SCI, 2.933; ranking: 28/88) (correspondent author).
  90. Lo Chi-Wei, Shang-Lin Chang & Ching-Feng Weng (2007) Pituitary adenylate cyclase-activating polypeptide (PACAP) regulates the expression of PACAP in cultured tilapia astrocyte. Exp. Biol. Med. (Maywood) 232: 262-76 (SCI, 2.845; ranking: 18/72) (correspondent author).

Patents

1. 張春生, 李松泰, 翁慶豐; 使用經由粉擬青黴菌G30801的培育而得到的產物來治療第一型或第二型糖尿病; TW Patent I376229; Nov, 2011.

2. 吳茂昆, 翁慶豐, 史閎元, 謝蕙雯; 含綬草萃取物的組合物及其醫藥應用; TW Patent I578991; Apr, 2017.

3. 翁慶豐, 賈宜琛, 邱韋鈞; 治療肺癌的方法及醫藥組合物; TW Patent I547279; Sep, 2016.

4. 翁慶豐, 賈宜琛, 吳嘉仁, 蔡湘儀; 用以預防及/或治療肝纖維化的方法及醫藥組合物; TW Patent I515002; Jan, 2016.

5. 翁慶豐, 李佳洪, 賈宜琛用於癌症治療之16-羥基克羅烷-3,13-二烯-15,16-內酯製劑; TW Patent 201630594; Sep, 2016.

6. Weng; Ching-Feng, Chia; Yi-Chen, Lee; Chia-Hung, Varadharajan; T.; HCD formulation for cancer treatment. US. Patent 9.682.003 A; Aug 25, 2016.

7. Weng; Ching-Feng, Chen; Chin-piao, Shivaji; Sulake Rohidas, Hsu; Chia-Yu; Compounds from Antrodia camphorate and their use in treatment of diabetes mellitus. US Patent 9.604.894; Jul 23, 2015.

8. Weng; Ching-Feng, Chen; Chin-piao, Chia; Yi-Chen, Hsu; Chia-Yu; Method and composition for treating diabetes mellitus. US Patent 9.226.950; May 14, 2015.

9. WU; Maw-Kuen; Weng, Ching-Feng; Shih, Hung-Yuan; Sie, Huei-Wun; Composition containing a spiranthes sinensis extract and pharmaceutical applications thereof. US Patent US20150250843A1; Sep,10, 2015.

 

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